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 Post subject: Re: Piles of Information
PostPosted: Sep 14th, '13, 14:32 
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SuperVeg wrote:
What is suppressed are (grammer?) drugs that might only make some profit.
It costs in the order of $500million and even up to $1billion just to get a drug approved by the FDA.


I think we may have a slightly different interpretation of the word "suppressed".

Pharmaceutical companies are in existence purely to make the maximum amount of profit possible.

I have never heard anyone claim they should be charities.

That's why we have the government funded institutions.

A company may have 100 new drugs in the pipeline at any one time, of which only one may be

worth investing $ billions to bring to market.

If they get two drugs, but only have the money for one, then they usually cross-licence one

of them with another company. That way they can have a revenue stream from both.

But they wouldn't hide it away, because someone else may discover it or something very similar.

Journeyman always likes to refer to the "Laws of Physics", now I like my physics and maths

but my Number one Law is "The Law of Common Sense"

If we apply common sense to the problem above:

A Pharmaceutical company synthesises two drugs, drug A and drug B.

expected revenue from Drug A is 80 billion

expected revenue from Drug B is only 10 billion

So, would the company shelve/suppress drug B and have a profit of 80 billion

Or, would it cross-licence drug B and have a total profit of 90 billion.

Remember its reason for existence is to make the maximum profit.

SuperVeg wrote:
10s of thousands of people die each year waiting for FDA drug approvals (that can take 15 years) for new drugs that could save their life.
Not to mention all the drugs they have approved and have killed people, yet the FDA is touted as the ONLY way to ensure safe drugs.


I can answer this with one word.

Thalidomide.


Some people think the approval agencies are too strict and some people think they are not strict enough.

To be honest, I'm not sure which is correct.

I know a cardiologist that doesn't prescribe new medication to her patients unless it has been on the market for three years.


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 Post subject: Re: Piles of Information
PostPosted: Sep 14th, '13, 15:21 
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Journeyman wrote:

An example is the 'pandemic' propaganda for the so-called swine flu, a flu that killed worldwide less than half the number of people just in the US who die from normal flu each year. The conspiracy? The propaganda ramped up so that Tamiflu became a major seller as symptom-reducer and preventative vaccine - right before Rumsfeld's millions of stored doses of Tamiflu were about to pass their use-by dates.




I can agree and disagree with you at the same time on this.

People get swine flu all the time, but usually they work with pigs and the transmission is pig to human.

What happened in 2009 the virus mutated so that it went from human to human.

The previous experience with the H1N1 mutation was The 1918 flu pandemic that killed 50 to 100 million people—3 to 5 percent of the world's population

At the beginning I think the people in charge were scared shiteless that it would be a repeat of 1918.

The fact it wasn't as severe, we were lucky but hindsight is a beautiful thing.

Did they take this opportunity to test their response procedures = absolutely

to off load their tamiflu, yes , but nobody actually made any extra money


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 Post subject: Re: Piles of Information
PostPosted: Sep 14th, '13, 15:46 
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Journeyman wrote:
But that wasn't the thing that caught my eye. What they found was, while blueberries were at the top of the list, their effect was way higher than the next candidate (strawberries from memory) AND they showed an interesting side effect. Blueberries not only have a powerful anti-free-radical effect, they found evidence some damage was being repaired in the cells.

And it worked on everything they could get a blueberry into. They stated extracts wouldn't do it, it had to be the whole berry. Dosage for the effect in humans was something like 8 - 12 blueberries per day.


Hi Jm
Are you sure it was blueberries ? and not billberry
Around here, american "bluberrys" have been markedet, and sold with those exact health effect arguments.
But it seems that it's a mixed identety wild billberries, are commonly called blueberrys, and the american blueberry is the one most people grow/buy, thinking/beliving it holds those super healthy effects.

I'm just asking cause I got fooled, like most other I know (marketing scam)

http://www.stevenfoster.com/education/m ... erry2.html

PS I'w forwarded your banana tips to my sister, if she decides to try it she promissed to share the results

cheers


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 Post subject: Re: Piles of Information
PostPosted: Sep 14th, '13, 15:52 
Bordering on Legend
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Journeyman wrote:

Dr Barry Marshall also got into rather a lot of trouble for his efforts because he infected himself with the bacteria to overcome the resistance to allowing his work. In fact, if you read the history of Dr Barry Marshall, it is a text book case to show how the anti-cure 'conspiracy' works. Ulcer treatments were a huge ongoing source of money and if you stopped the treatments you got the ulcers back - money in the hip pocket for Big Pharma.

Probably not a good source to try to make your point. :D The lengths he had to go to to get his & Warren's work published, let alone accepted, shows a definite resistance to anything that might cure rather than provide an ongoing income for the Big Pharma.



"Not a good source to try to make your point"

I think it is the BEST source to make my point.

Dr Marshall proposed a theory that ulcers are caused by bacteria and not stress.

In 1984 he tried to prove it by infecting piglets with the bacteria.

But it did not work.

For his work to be accepted by his peers IT NEEDS TO BE BEYOND ALL DOUBT.

not just reasonable doubt. He only got solid evidence after infecting himself.

(By the way he didn't need to infect himself, there are other ways to test it. He took a short cut)

I would argue his peers showed a proper degree of scientific scepticism until his theory could be supported by evidence.

If they hadn't shown this degree of scepticism they would have to accept work from any

charlatan, witch doctor, snake oil salesman or quack such as Hulda Clark or Dr Ryke Geerd Hamer


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 Post subject: Re: Piles of Information
PostPosted: Sep 14th, '13, 17:19 
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SolTun wrote:
Hi Jm
Are you sure it was blueberries ? and not billberry
Around here, american "bluberrys" have been markedet, and sold with those exact health effect arguments.
But it seems that it's a mixed identety wild billberries, are commonly called blueberrys, and the american blueberry is the one most people grow/buy, thinking/beliving it holds those super healthy effects.

I'm just asking cause I got fooled, like most other I know (marketing scam)

http://www.stevenfoster.com/education/m ... erry2.html

PS I'w forwarded your banana tips to my sister, if she decides to try it she promissed to share the results

cheers

Pretty sure it was blueberries, but I don't recall seeing if there was mention of a type of blueberries. I've never heard of billberries so unless I misread all the way through the article it was blueberries.

The article below isn't the one I recall but is saying something very similar.
[quote=A Radical Proposal]. Last year neuroscientist James A. Joseph of Tufts University and his colleagues reported that middle-aged rats fed extracts of spinach, blueberries or strawberries for eight weeks showed marked declines in
oxidative stress in their brain cells, as well as improved memory and coordination.

The most successful rats noshed on blueberries—the equivalent of a cup a day for humans.

The research also highlights how much scientists have to learn about the processes that contribute to aging. Apparently, it’s the blend of ingredients inside blueberries—not just isolated antioxidants—that benefited the racy rats.

Studying the rats’ brain cells, Joseph was surprised to find relatively few signs of increased antioxidants. Instead he found a host of cell changes, from better antiinflammatory activity to more pliable membranes—all of which could act together to combat aging changes.
“If you take a supplement, you never get the benefit of a fruit or vegetable that contains hundreds of compounds,”[/quote]


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 Post subject: Re: Piles of Information
PostPosted: Sep 14th, '13, 18:00 
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Hi again

Vaccinium myrtillus (bilberry) is a member of the Ericaceae family, and is also known as European blueberry, huckleberry, whortleberry, or blueberry.
It is a shrubby perennial plant one to two feet in height and can be found in the mountains and forests of Europe and the northern United States.
Its branches contain alternating, elliptical, bright green leaves, and its flowers, which appear from April to June, are reddish or pink, and bell-shaped.
The fruit of the bilberry plant is blue-black or purple and differs from the American blueberry in that the meat of the fruit is purple, rather than cream or white.

Quote from this doc. : http://www.thorne.com/altmedrev/.fulltext/6/5/500.pdf

It's common to use the name blueberry on bilberries, my sister is a herbalist she was the one educating me on the intermix of blueberrys vs blueberrys

cheers

Quote from here : http://en.wikipedia.org/wiki/American_blueberry

Origins

The genus Vaccinium has a mostly circumpolar distribution with species in America, Europe, Asia, and Africa.

Many commercially sold species with English common names including "blueberry" are currently classified in section Cyanococcus of the genus Vaccinium and come predominantly from North America. Many North American native species of blueberries are grown commercially in the Southern Hemisphere in Australia, New Zealand and South American countries.

Several other wild shrubs of the genus Vaccinium also produce commonly eaten blue berries, such as the predominantly European Vaccinium myrtillus and other bilberries, that in many languages have a name that translates "blueberry" in English. See the Identification section for more information.


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 Post subject: Re: Piles of Information
PostPosted: Sep 14th, '13, 18:17 
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As for nobody making money from Tamiflu...
Quote:
Sales of anti-flu drug Tamiflu soared 203 percent in the first six months of 2009, Swiss pharmaceutical giant Roche said Thursday, contributing to a 9.0 percent growth in overall sales for the group.

Amid the swine flu pandemic, sales of the drug reached 1.0 billion Swiss francs (938 million US dollars or 659 million euros) in the first half of the year.

Sales to governments and corporations which were stockpiling the drug reached 653 million francs during the period, said Roche.

"Additional government stockpiling orders and increased demand in the retail pharmacy market contributed to the particularly strong sales recorded in the second quarter," it added.

Advertisement
Roche said it would be ramping up its production capacity of Tamiflu -- one of two drugs recommended by the World Health Organisation to treat the A(H1N1) virus -- to 400 million packs annually by 2010.
Seems tha facts disagree. :D

As for hindsight, swine flu wasn't even dangerous in foresight - the propaganda started long before any deaths occurred.

The transmission vectors looked nothing like a normal flu distribution.

The genetics suggested from the start this was a laboratory creation.

It was a deliberately created pandemic scare designed from the start to sell millions of doses of almost out -of-date Tamiflu that would otherwise have been a significant loss of money.

For the conspiracy side of it, just look at the fact that all official sources were touting swine flu as a possible deadly epidemic on what we can easily see (with your hindsight) was no evidence whatsoever. Not only is that irresponsible it is against almost all we know of flu viruses. If a virus is virulent (highly infectious) it is not deadly; if it is deadly it is not virulent.

Of course, it is possible that someone might make a virus that is virulent AND deadly, just like a lab or two who were trying to combine standard flu virus with something far more deadly after swine flu scare tactics abated. Even recently a Chinese lab has been deliberately making 127 variants of bird flu that will be/are both deadly AND virulent.

The very studies that report on such events tell more than is reported in the MSM.
Quote:
Preliminary genetic characterization found that the hemagglutinin (HA) gene was similar to that of swine flu viruses present in U.S. pigs since 1999, but the neuraminidase (NA) and matrix protein (M) genes resembled versions present in European swine flu isolates.
The six genes from American swine flu are themselves mixtures of swine flu, bird flu, and human flu viruses.[21]
While viruses with this genetic makeup had not previously been found to be circulating in humans or pigs, there is no formal national surveillance system to determine what viruses are circulating in pigs in the U.S.

So the 'pandemic' version of flu has genetics from very different areas of the planet, it mixes not 2 but 3 different flu types and there is no apparent development path historically.

Even worse, the propagation begins in yet another country, (Mexico) so we can't even say there was some kind of 'natural' cause. Yes, I cannot prove H1N1 was deliberately seeded, but equally it is quite clear from the evidence something extraordinary has happened.

Given the regularity with which pathogens escape labs (H1N1 or H7N9 anyone?) PLUS the ethical considerations of deliberately making something designed to wipe out a maximum number of people in shortest time, one would have to question the sanity of the scientists involved...


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 Post subject: Re: Piles of Information
PostPosted: Sep 14th, '13, 18:24 
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Not sure what happened to the post prior to Soltun's last - it was meant to look like this...

SolTun wrote:
Hi Jm
Are you sure it was blueberries ? and not billberry
Around here, american "bluberrys" have been markedet, and sold with those exact health effect arguments.
But it seems that it's a mixed identety wild billberries, are commonly called blueberrys, and the american blueberry is the one most people grow/buy, thinking/beliving it holds those super healthy effects.

I'm just asking cause I got fooled, like most other I know (marketing scam)

http://www.stevenfoster.com/education/m ... erry2.html

PS I'w forwarded your banana tips to my sister, if she decides to try it she promissed to share the results

cheers

Pretty sure it was blueberries, but I don't recall seeing if there was mention of a type of blueberries. I've never heard of billberries so unless I misread all the way through the article it was blueberries.

The article below isn't the one I recall but is saying something very similar.
. Last year neuroscientist James A. Joseph of Tufts University and his colleagues reported that middle-aged rats fed extracts of spinach, blueberries or strawberries for eight weeks showed marked declines in
oxidative stress in their brain cells, as well as improved memory and coordination.

The most successful rats noshed on blueberries—the equivalent of a cup a day for humans.

The research also highlights how much scientists have to learn about the processes that contribute to aging. Apparently, it’s the blend of ingredients inside blueberries—not just isolated antioxidants—that benefited the racy rats.

Studying the rats’ brain cells, Joseph was surprised to find relatively few signs of increased antioxidants. Instead he found a host of cell changes, from better antiinflammatory activity to more pliable membranes—all of which could act together to combat aging changes.
“If you take a supplement, you never get the benefit of a fruit or vegetable that contains hundreds of compounds,”

Also from another source,
Ample research indicates that age-related neuronal–behavioral decrements are the result of oxidative stress that may be ameliorated by antioxidants. Our previous study had shown that rats given dietary supplements of fruit and vegetable extracts with high antioxidant activity for 8 months beginning at 6 months of age retarded age-related declines in neuronal and cognitive function.

The present study showed that such supplements (strawberry, spinach, or blueberry at 14.8, 9.1, or 18.6 gm of dried aqueous extract per kilogram of diet, respectively) fed for 8 weeks to 19-month-old Fischer 344 rats were also effective in reversing age-related deficits in several neuronal and behavioral parameters including: oxotremorine enhancement of K1-evoked release of dopamine from striatal slices, carbachol-stimulated GTPase activity, striatal Ca45 buffering in striatal synaptosomes, motor behavioral performance on the rod walking and accelerod tasks, and Morris water maze performance.

These findings suggest that, in addition to their known beneficial effects on cancer and heart disease, phytochemicals present in antioxidant-rich foods may be beneficial in reversing the course of neuronal and behavioral aging.


@Soltun - I've never seen blueberries that don't have very dark flesh and the pics in the article were, to me, blueberries so I presume they were talking the European type rather than ones that don't have the dark flesh. IIRC there was a correlation they saw between darkness of colour and the level of benefit.


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 Post subject: Re: Piles of Information
PostPosted: Sep 14th, '13, 19:36 
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trout wrote:

I think we may have a slightly different interpretation of the word "suppressed".

Pharmaceutical companies are in existence purely to make the maximum amount of profit possible.

Like every other company, profit is not a bad thing in a free market (It can be with govt connected industries like big pharma though)
Quote:

I have never heard anyone claim they should be charities.
I wasn't

Quote:
A company may have 100 new drugs in the pipeline at any one time, of which only one may be

worth investing $ billions to bring to market.

If they get two drugs, but only have the money for one, then they usually cross-licence one

of them with another company. That way they can have a revenue stream from both.

But they wouldn't hide it away, because someone else may discover it or something very similar.

I was just talking about smaller startups etc with lifesaving treatments.

. Delay of life saving technologies. It often takes over 10-15 years to get approval!
How many people die because they cannot get access to these treatments.
Nobody risks their job in FDA by saying “no”, only “yes”
The review boards are a joke. They consist mainly of your potential competitors!

2. "Needless paperwork. At least half of my company’s expenses are directly related to useless compliance with FDA paperwork. "

3. Chilling effect on new products and technologies. Want to make venture capital run away and hide? Say “subject to FDA approval”


And its getting worse, they want to make vitamins subject to FDA approval don't they ??
Quote:
SuperVeg wrote:
10s of thousands of people die each year waiting for FDA drug approvals (that can take 15 years) for new drugs that could save their life.
Not to mention all the drugs they have approved and have killed people, yet the FDA is touted as the ONLY way to ensure safe drugs.


I can answer this with one word.

Thalidomide.


And there are a lot more
Quote:


Some people think the approval agencies are too strict and some people think they are not strict enough.

To be honest, I'm not sure which is correct.

That's the problem with this sort of regulation, often it can be too restrictive, but potentially even more damaging is the false sense of security regulations. When they are not safe enough it can be very dangerous. Like Thalidomide.
Quote:
I know a cardiologist that doesn't prescribe new medication to her patients unless it has been on the market for three years.


I think this is a clue to the solution.
I think the FDA should be abolished. What will happen then will be the formation of competitive standards agencies, this happens in many other industries. Patients and their doctors can then choose the level of safety they want in their treatments. A pregnant mother might want the absolute highest level of safety for her morning sickness drugs.
A person on the brink of death from cancer would probably be willing to bypass almost all safety standards just to have a small chance of living for a bit longer. He should have that right.

What do you think ?


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 Post subject: Re: Piles of Information
PostPosted: Sep 14th, '13, 22:36 
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Huckleberries are an orangish pink color, not blue. I remember picking them a a kid... Usually when out blackberry picking, it was always nice to come across a huckleberry bush.


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 Post subject: Re: Piles of Information
PostPosted: Sep 14th, '13, 23:28 
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Ronmaggi wrote:
Huckleberries are an orangish pink color, not blue. I remember picking them a a kid... Usually when out blackberry picking, it was always nice to come across a huckleberry bush.


Hi
You are talking about yet another variant probabbly this :
http://en.wikipedia.org/wiki/Vaccinium_parvifolium
or maybe this (most common in northern europe) :
http://en.wikipedia.org/wiki/Vaccinium_vitis-idaea
the last is bitter/souer comparred to bilberry, I use both, as sweet & souer when serving game dishes

cheers


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 Post subject: Re: Piles of Information
PostPosted: Sep 14th, '13, 23:29 
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It was not sour... It was most certainly sweet. But yes, it was the first link. I grew up in that area.


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 Post subject: Re: Piles of Information
PostPosted: Sep 15th, '13, 01:35 
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SuperVeg wrote:
I was just talking about smaller startups etc with life saving treatments.

. Delay of life saving technologies. It often takes over 10-15 years to get approval!
How many people die because they cannot get access to these treatments.
Nobody risks their job in FDA by saying “no”, only “yes”
The review boards are a joke. They consist mainly of your potential competitors!

2. "Needless paperwork. At least half of my company’s expenses are directly related to useless compliance with FDA paperwork. "

3. Chilling effect on new products and technologies. Want to make venture capital run away and hide? Say “subject to FDA approval”


And its getting worse, they want to make vitamins subject to FDA approval don't they ??


I can't really talk about the FDA (as I have no experience) but I think the Australian system is quite good.

Paperwork is part and parcel of the game.

And the regulatory game is designed to weed out the conmen, quacks and charlatans such as

Hulda Clark or Dr Ryke Geerd Hamer.

The FDA or TGA offer the consumer a type of safety net of information.

A consumer with no understanding of medicine can be assured that the TGA approved

medication actually does what it claims it can do.

Your first point about delays of life saving treatments I think is extreme. If a treatmentt is seen to be extremely

effective during trials it will be fast tracked. ( I would assume the FDA has similar provisions.)


SuperVeg wrote:
I think the FDA should be abolished. What will happen then will be the formation of competitive standards agencies, this happens in many other industries. Patients and their doctors can then choose the level of safety they want in their treatments. A pregnant mother might want the absolute highest level of safety for her morning sickness drugs.
A person on the brink of death from cancer would probably be willing to bypass almost all safety standards just to have a small chance of living for a bit longer. He should have that right.

What do you think ?


What do I think, abolish the FDA and establish competitive standards agencies.

Aren't you setting up another FDA, just under a different name?


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 Post subject: Re: Piles of Information
PostPosted: Sep 15th, '13, 01:58 
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SuperVeg wrote:
Delay of life saving technologies. It often takes over 10-15 years to get approval!
How many people die because they cannot get access to these treatments.
Nobody risks their job in FDA by saying “no”, only “yes”
The review boards are a joke. They consist mainly of your potential competitors!


I thought this deserves a post of its own.


Quote:
Fifty years ago, the vigilance of FDA medical officer Dr. Frances Kelsey prevented a public health tragedy of enormous proportion by ensuring that the sedative thalidomide was never approved in the United States - See more at: http://blogs.fda.gov/fdavoice/index.php ... 6JJJV.dpuf


Frances Kelsey never buckled, even under pressure from the company.

She stood her ground and said NO.

Thousands and thousands of people in America today need to thank her.


I might just add a few more quotes from the article.


Quote:
Now I know that in some circles regulation is viewed as a roadblock to innovation and economic growth. But in actuality, when done right, regulation isn’t a roadblock; it’s the actual pathway to achieving real and lasting innovation.

Smart, science-based regulation instills consumer confidence in products and treatments. It levels the playing field for businesses. It decreases the threat of litigation. It prevents recalls that threaten industry reputation and consumer trust, not to mention levying huge preventable costs on individual companies and entire industries. And it spurs industry to excellence
- See more at: http://blogs.fda.gov/fdavoice/index.php ... 6JJJV.dpuf


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 Post subject: Re: Piles of Information
PostPosted: Sep 15th, '13, 02:22 
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Journeyman wrote:
As for nobody making money from Tamiflu...

Seems the facts disagree. :D


Not quite.

The stockpile of Tamiflu was near its exp date. From memory one batch was past its exp date

but was tested, found to be within potency and given an extension.

The doses were given to patients for free.

Any doses not used were discarded and fresh supplies purchased.

This turnover of medication would have occurred regardless of the swine flu.

And will occur again in 3-4 years.


Journeyman wrote:
As for hindsight, swine flu wasn't even dangerous in foresight - the propaganda started long before any deaths occurred.

The transmission vectors looked nothing like a normal flu distribution.

The genetics suggested from the start this was a laboratory creation.

It was a deliberately created pandemic scare designed from the start to sell millions of doses of almost out -of-date Tamiflu that would otherwise have been a significant loss of money.


This whole paragraph is wrong.



Journeyman wrote:
If a virus is virulent (highly infectious) it is not deadly; if it is deadly it is not virulent.


This statement is completely wrong and the 50 to 100 million people that died from the H1N1

in 1918 would beg to differ.

Journeyman wrote:
For the conspiracy side of it, just look at the fact that all official sources were touting swine flu as a possible deadly epidemic on what we can easily see (with your hindsight) was no evidence whatsoever. Not only is that irresponsible it is against almost all we know of flu viruses.



Oh Crap

It looks like everybody in the world is involved in some worldwide conspiracy except me.

:cry:


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